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Tocris Bioscience™ KYL
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Catalog No. 52901
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Catalog No. Quantity
52-901 1 mg
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Catalog No. 52-901 Supplier Tocris Bioscience™ Supplier No. 5290/1
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Description

EphA4 kinase inhibitor; neuroprotective

KYL is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.

Specifications

Description KYL
Molecular Weight (g/mol) 1465.75
Product Type KYL
Quantity 1 mg
Sequence Lys-Tyr-Leu-Pro-Tyr-Trp-Pro-Val-Leu-Ser-Ser-Leu

For Research Use Only

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