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  8. L-165,041, Tocris Bioscience™

L-165,041, Tocris Bioscience™

Catalog No. 185650
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Catalog No. Quantity
18-565-0 50 mg
18-561-0 10 mg
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Catalog No. 18-565-0 Supplier R&D Systems Supplier No. 1856/50
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Description

Potent PPARδ agonist

Potent PPARδ agonist (Ki = 6 nM); displays > 100-fold selectivity for both mouse and human PPARδ receptors over other subtypes. Raises plasma cholesterol levels in vivo, in insulin-resistant db/db mice. Neuroprotective in models of cerebral infarction and Parkinson's disease.

Chemical Identifiers

CAS 79558-09-1
Molecular Formula C22H26O7
Molecular Weight (g/mol) 402.443
InChI Key HBBVCKCCQCQCTJ-UHFFFAOYSA-N
Synonym 2-4-3-4-acetyl-3-hydroxy-2-propylphenoxy propoxy phenoxy acetic acid, 4-3-4-acetyl-3-hydroxy-2-propylphenoxy propoxy phenoxy-acetic acid, 4-3-4-acetyl-3-hydroxy-2-propylphenoxy propoxy phenoxyacetic acid, 2-4-3-4-acetyl-3-hydroxy-2-propylphenoxy-propoxy phenoxy acetic acid, 4-3-4-acetyl-3-hydroxy-2-propylphenoxy propoxy phenoxy acetic acid, 4-3-2-propyl-3-hydroxy-4-acetyl phenoxy propyloxyphenoxy-acetic acid, aceticacid, 2-4-3-4-acetyl-3-hydroxy-2-propylphenoxy propoxy phenoxy, pubchem19280, lopac-l-2167
PubChem CID 6603901
IUPAC Name 2-[4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]acetic acid
SMILES CCCC1=C(C=CC(=C1O)C(=O)C)OCCCOC2=CC=C(C=C2)OCC(=O)O

Specifications

Quantity 50 mg
Formula Weight 402.44
Percent Purity >98%
Chemical Name or Material L-165, 041

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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