L-Glutathione, oxidized

Description

Acts as hydrogen acceptor in enzymatic determination of NADP and NADPH | CAS: 27025-41-8 | C20H32N6O12S2 | 612.63 g/mol

L-Glutathione is used as a Acts as hydrogen acceptor in enzymatic determination of NADP and NADPH, it is used to reduced back to glutathione (GSH) via the NADPH-dependent enzyme glutathione reductase. The ratio of GSH to GSSG is often used to gauge the level of oxidative stress in cells, with higher concentrations of GSSG implying more oxidative stress

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
L-Glutathione is used as a Acts as hydrogen acceptor in enzymatic determination of NADP and NADPH, it is used to reduced back to glutathione (GSH) via the NADPH-dependent enzyme glutathione reductase. The ratio of GSH to GSSG is often used to gauge the level of oxidative stress in cells, with higher concentrations of GSSG implying more oxidative stress

Solubility
Soluble in water, DMF, and ethanol.

Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 27025-41-8
• Molecular Formula: C20H32N6O12S2
• Molecular Weight (g/mol): 612.63
• MDL Number: MFCD00150701
• InChI Key: YPZRWBKMTBYPTK-IOKZUGQQNA-N
• Synonym: oxiglutatione, glutathione disulfide, gssg, oxidized glutathione, glutathione disulphide, glutathione-ssg, l-glutathione oxidized, oxigluthione, glutathone disulfide, glutathione oxidized
• PubChem CID: 65359
• ChEBI: CHEBI:17858
• IUPAC Name: (2S)-2-amino-5-[[(2R)-3-[[(2R)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]-3-(carboxymethylamino)-3-oxopropyl]disulfanyl]-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
• SMILES: N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O

• Color: White
• Quantity: 1 g
• Beilstein: 1718700
• Merck Index: 14,4475
• Solubility Information: Soluble in water,DMF,and ethanol.
• Optical Rotation: −105° (c=2 in Water)
• Formula Weight: 612.64
• Physical Form: Powder
• Chemical Name or Material: L-Glutathione, oxidized

Safety and Handling

Hazard Category	Warning
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	GHS P Statement P261-P280-P305+P351+P338-P304+P340-P405-P501a Avoid breathing dust/fume/gas/mist/vapors/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
EINECSNumber	248-170-7
RTECSNumber	MC0556500
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only