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Abcam L-Mimosine, Non-protein Amino Acid, >98% Purity, Solid, 250 mg

Catalog No. 502705070
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50-270-5070 250 mg
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Catalog No. 50-270-5070 Supplier Abcam Supplier No. AB145861250MG
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Description

Toxic non-protein amino acid that arrests the cell cycle by inhibiting deoxyribonucleotide metabolism and chelating iron.

  • Molecular Weight: 198.18 g/mol
  • Purity: >98%
  • Form: Solid
  • Description: Toxic non-protein amino acid originally isolated from Mimosa pudica.
  • Mechanism of Action: Arrests cell cycle at the G1 phase in PC-3 cells and at the S phase in LNCaP cells; blocks cell cycle progression by chelating iron; inhibits DNA synthesis by inhibiting deoxyribonucleotide metabolism; acts as a prolyl hydroxylase (PHD) inhibitor.
  • Storage Temperature: Store at -20°C.
  • Chemical Formula: (S)-α-Amino-3-hydroxy-4-oxo-1(4H)-pyridylpropionic acid

Specifications

Target Molecule Prolyl Hydroxylase
Substrate Properties Chemical Substrate
Shipping Condition Ambient
Buffer (S)-α-Amino-3-hydroxy-4-oxo-1(4H)-pyridylpropionic acid
Content And Storage Store at -20°C.
Form Solid
Formulation 100% (S)-α-Amino-3-hydroxy-4-oxo-1(4H)-pyridylpropionic acid
Quantity 250 mg
For Use With (Application) Cell cycle arrest, DNA synthesis inhibition, Prolyl hydroxylase inhibition
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