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  6. Epredia™ Lab Vision™ ALK (Anaplastic Lymphoma Kinase)/p80 Rabbit Monoclonal Antibody

Epredia™ Lab Vision™ ALK (Anaplastic Lymphoma Kinase)/p80 Rabbit Monoclonal Antibody

Catalog No. p-4536137 Shop All Epredia Products
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Quantity:
100 μL
1 mL
12 mL
Form:
Concentrated
Prediluted
Ready-to-Use
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RM9108S0 100 μL Concentrated
RM9108R1 1 mL Prediluted
RM9108RQ 12 mL Ready-to-Use
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Description

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ ALK (Anaplastic Lymphoma Kinase)/p80, Rabbit Monoclonal Antibody.

Recognizes a human p80 protein, identified as a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in 30-50% of CD30+ large cell lymphomas (1). This rabbit monoclonal antibody can be used to detect p80 in these lymphomas and may also be used to detect a recently described subtype of large B cell lymphoma, which expresses the full-length ALK protein (2).

Host Species: Rabbit

Clone: SP8

Isotype: IgG

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Recombinant protein corresponding to a region which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript

Positive Control: Anaplastic lymphoma

Cellular Localization: Cytoplasmic + nuclear Clone SP8 is excellent for staining of formalin/paraffin with no special pretreatment

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Antigen ALK (Anaplastic Lymphoma Kinase)/p80
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SP8
Conjugate Unconjugated
Host Species Rabbit
Immunogen Recombinant protein corresponding to a region, which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript
Quantity 100 μL
Regulatory Status IVD
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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