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  6. Epredia™ Lab Vision™ β-Catenin Rabbit Monoclonal Antibody

Epredia™ Lab Vision™ β-Catenin Rabbit Monoclonal Antibody

Catalog No. RM2101S Shop All Epredia Products
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Quantity:
100 μL
1 mL
12 mL
Form:
Concentrated
Ready-to-Use
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Catalog No. Quantity Form
RM2101S 1 mL Concentrated
RM2101S0 100 μL Concentrated
RM2101RQ 12 mL Ready-to-Use
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Description

Ensure accurate and reproducible results in immunohistochemistry applications with this antibody, part of a comprehensive antibody portfolio.

The catenins (α, β and γ) are ubiquitously expressed cytoplasmic proteins associated with E-cadherin at cellular junctions. β-catenin also binds to N-cadherin and co-immunoprecipitates with APC. Cadherin/catenin complexes are linked to the cytoskeleton via a direct association between α-actinin and α-catenin. Increased tyrosine phosphorylation can disrupt catenin-cadherin complexes, influencing cellular adhesion. Mutations in the catenin gene, CTNNB1, have been implicated in its accumulation and various forms of carcinomas.

Host Species: Rabbit

Clone: E247

Species Reactivity: Human. Others not known.

Immunogen: A synthetic peptide derived from near the N-terminus of human β-catenin

Molecular Weight: 92 kDa

Positive Control: Breast CA

Cellular Localization: Cell Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Antigen Catenin, beta
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone E247
Conjugate Unconjugated
Host Species Rabbit
Immunogen A synthetic peptide derived from near the N-terminus of human beta-catenin
Quantity 1 mL
Regulatory Status IVD
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Human
Form Concentrated
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