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CD137 (4-1BB) Ab-1 Mouse Monoclonal Antibody, Epredia™

Epredia™ CD137 (4-1BB) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

Specifications

Antigen	CD137 Ab-1
Clone	BBK-2
Applications	Flow Cytometry, Immunofluorescence
Classification	Monoclonal
Form	Concentrated

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Products 7

Catalog Number	Mfr. No.	Conjugate	Concentration	Quantity	Price	Quantity & Availability
Catalog Number	Mfr. No.	Conjugate	Concentration	Quantity	Price	Quantity & Availability
MS621B0 View Documents View Product Certificates View Alternatives and Save Up to	Epredia MS621B0	Biotin	200μg/mL	100 μL	N/A		N/A	N/A

MS621B1 View Documents View Product Certificates View Alternatives and Save Up to	Epredia MS621B1	Biotin	200μg/mL	500 μL	N/A		N/A	N/A

MS621B View Documents View Product Certificates View Alternatives and Save Up to	Epredia MS621B	Biotin	200μg/mL	1 mL	N/A		N/A	N/A

MS621P0 View Documents View Product Certificates View Alternatives and Save Up to	Epredia MS621P0	Unconjugated	200μg/mL	100 μL	N/A		N/A	N/A

MS621P1 View Documents View Product Certificates View Alternatives and Save Up to	Epredia MS621P1	Unconjugated	200μg/mL	500 μL	N/A		N/A	N/A

MS621P1ABX View Documents View Product Certificates View Alternatives and Save Up to	Epredia MS621P1ABX	Unconjugated	1mg/mL	100 μL	N/A		N/A	N/A

MS621PABX View Documents View Product Certificates View Alternatives and Save Up to	Epredia MS621PABX	Unconjugated	1mg/mL	200 μL	N/A		N/A	N/A

Description

4-1BB (also known as CD137) is an inducible receptor-like protein expressed on the cell surface of activated splenic T cells and thymocytes. It exists as both a monomer and a dimer on the surface of activated T cells. 4-1BB is structurally related to the members of NGFR/TNFR superfamily which are characterized by the presence of three-six patterns of a cysteine-rich motif in their extracellular domains. Other members of this family include low affinity NGFR, two receptors for TNF (TNFR-I & TNFR-II), CD30, CD40, OX40, Fas, and CD27. These molecules are involved in cell growth, survival, and death processes. The cytoplasmic domain of 4-1BB include two runs of acidic amino acids, a potential p56^lck binding site, five consecutive glycines at the C-terminus, and four potential phosphorylation sites: one tyrosine, two threonine, and one serine.

Host Species: Mouse

Clone: BBK-2

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Ectodomain

Immunogen: Ectodomain of human 4-1BB recombinant protein

Molecular Weight: 30kDa

Positive Control: Spleen, thymus or tonsil

Cellular Localization: Membrane

Recommended for:

Immunofluorescence
Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen	CD137 Ab-1
Applications	Flow Cytometry, Immunofluorescence
Form	Concentrated
Regulatory Status	RUO
Target Species	Human
Isotype	IgG1 κ

Clone	BBK-2
Classification	Monoclonal
Host Species	Mouse
Research Discipline	Apoptosis
Immunogen	Ectodomain of human 4-1BB recombinant protein
Primary or Secondary	Primary

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CD137 (4-1BB) Ab-1 Mouse Monoclonal Antibody, Epredia™

Specifications

Description

Specifications

Documents