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  6. CD137 (4-1BB) Ab-1 Mouse Monoclonal Antibody, Epredia™

CD137 (4-1BB) Ab-1 Mouse Monoclonal Antibody, Epredia™

Catalog No. p-4547015 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Conjugate:
Biotin
Unconjugated
Concentration:
1mg/mL
200μg/mL
7 product options available for selection
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Catalog No. Quantity Conjugate Concentration
MS621B0 100 μL Biotin 200μg/mL
MS621B1 500 μL Biotin 200μg/mL
MS621B 1 mL Biotin 200μg/mL
MS621P0 100 μL Unconjugated 200μg/mL
MS621P1 500 μL Unconjugated 200μg/mL
MS621P1ABX 100 μL Unconjugated 1mg/mL
MS621PABX 200 μL Unconjugated 1mg/mL
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Catalog No. MS621B0 Supplier Epredia Supplier No. MS621B0

Description

Epredia™ CD137 (4-1BB) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

4-1BB (also known as CD137) is an inducible receptor-like protein expressed on the cell surface of activated splenic T cells and thymocytes. It exists as both a monomer and a dimer on the surface of activated T cells. 4-1BB is structurally related to the members of NGFR/TNFR superfamily which are characterized by the presence of three-six patterns of a cysteine-rich motif in their extracellular domains. Other members of this family include low affinity NGFR, two receptors for TNF (TNFR-I & TNFR-II), CD30, CD40, OX40, Fas, and CD27. These molecules are involved in cell growth, survival, and death processes. The cytoplasmic domain of 4-1BB include two runs of acidic amino acids, a potential p56lck binding site, five consecutive glycines at the C-terminus, and four potential phosphorylation sites: one tyrosine, two threonine, and one serine.

Host Species: Mouse

Clone: BBK-2

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Ectodomain

Immunogen: Ectodomain of human 4-1BB recombinant protein

Molecular Weight: 30kDa

Positive Control: Spleen, thymus or tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunofluorescence
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen CD137 Ab-1
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone BBK-2
Concentration 200μg/mL
Conjugate Biotin
Host Species Mouse
Immunogen Ectodomain of human 4-1BB recombinant protein
Quantity 100 μL
Regulatory Status RUO
Research Discipline Apoptosis
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG1 κ
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