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DOG1 Mouse Monoclonal Antibody, Epredia™

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ Dog1, Mouse Monoclonal Antibody.

$162.00 - $717.00

Specifications

Antigen Dog1
Clone 1.1
Applications Immunohistochemistry
Conjugate Unconjugated
Host Species Mouse
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Products 5
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
MS1933P
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Epredia
MS1933P
Purified Ab with BSA and Azide 1mL
Each for $717.00
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MS1933P0
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Epredia
MS1933P0
Purified Ab with BSA and Azide 100μL
Each for $162.00
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MS1933R7
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Epredia
MS1933R7
Ready-to-use for IHC (UVLP) 7mL
Each for $405.00
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MS1933R1
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Epredia
MS1933R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. View substitute products »
MS1933RQ
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Epredia
MS1933RQ
Ready-to-use for IHC (Quanto) 12mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

DOG1 is a cell surface protein of unknown function selectively expressed in gastrointestinal stromal tumors (GIST). Among GIST cases with KIT mutations the DOG1 antibody identified 11% more cases than c-Kit antibody1. DOG1 identifies vast majority of both c-Kit negative and PDGFRA mutated GIST cases that may still benefit from imatinib mesylate (Gleevac), an inhibitor of the kit tyrosine kinase2. In addition, DOG1 immunoreactivity is seen in fewer cases of mesanchymal, epithelial tumors and melanomas when compared with c-Kit. The use of this highly sensitive and specific novel marker will increase the accuracy of GIST diagnosis.

Host Species: Mouse

Clone: 1.1

Isotype: Unknown

Species Reactivity: Human. Others not known.

Immunogen: Synthetic peptide of human DOG1

Molecular Weight: 78 kDa

Positive Control: Gastrointestinal Stromal Tumors

Cellular Localization: Cytoplasmic and Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Specifications

Dog1
Immunohistochemistry
Mouse
Synthetic peptide of human Dog1
1.1
Unconjugated
Primary
SDS
Product Certifications
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