Epidermal Growth Factor Receptor/EGFR Ab-11 Mouse Monoclonal Antibody, Epredia™

Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments.

Catalog Number	Mfr. No.	Concentration	Quantity
MS396P1	Epredia MS396P1	200μg/mL	500 μL
MS396P1ABX	Epredia MS396P1ABX	1mg/mL	100 μL
MS396P0	Epredia MS396P0	200μg/mL	100 μL
MS396P	Epredia MS396P	200μg/mL	1 mL
MS396PABX	Epredia MS396PABX	1mg/mL	200 μL

Description

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 199.12

Isotype: IgG2a

Species Reactivity: Human. Others not known.

Epitope: Extracellular domain

Immunogen: Extracellular domain of human recombinant EGFR protein

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells

Cellular Localization: Membrane

Recommended for:

• Western Blotting
• Immunoprecipitation (Native only)
• Effect on EGF Binding (Noninhibitory)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Epidermal Growth Factor Receptor/EGFR Ab-11
• Classification: Monoclonal
• Form: Concentrated
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG2a

• Clone: 199.12
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: EGFR Family
• Immunogen: Extracellular domain of human recombinant EGFR protein
• Primary or Secondary: Primary