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Ku (p70) Ab-4 Mouse Monoclonal Antibody, Epredia™

Recommended for multiple molecular biology techniques, Epredia™ Ku (p70) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.

Specifications

Antigen Ku (p70) Ab-4
Clone N3H10
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Conjugate Unconjugated
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Products 7
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
MS329P
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Epredia
MS329P
Purified Ab with BSA and Azide 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
MS329R1
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Epredia
MS329R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
MS329P0
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Epredia
MS329P0
Purified Ab with BSA and Azide 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
MS329P1
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Epredia
MS329P1
Purified Ab with BSA and Azide 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
MS329P1ABX
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Epredia
MS329P1ABX
Ab without BSA/Azide (Frozen) 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
MS329PABX
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Epredia
MS329PABX
Ab without BSA/Azide (Frozen) 200μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
MS329R7
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Epredia
MS329R7
Ready-to-use for IHC (UVLP) 7mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

The Ku autoantigen is a heterodimer of 70kDa (p70) and ∽80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Host Species: Mouse

Clone: N3H10

Isotype: IgG2b

Species Reactivity: Human, Monkey and Xenopus. Mouse and Hamster (Western Blotting only). Does not react with cow, rabbit and sea urchin.

Epitope: aa 506-541

Immunogen: Human placental extract designated as PSE1-PL

Molecular Weight: 70kDa

Positive Control: BT474, T47D, HEP-G-2 or HeLa cells; Tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Ku (p70) Ab-4
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
RUO
Primary
IgG2b
N3H10
Monoclonal
Mouse
DNA Repair
Human placental extract designated as PSE1-PL
SDS
Product Certifications
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