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LRP/MVP (Major Vault Protein) Ab-2 Mouse Monoclonal Antibody, Epredia™

Recommended for a variety of techniques, Epredia™ LRP/MVP (Major Vault Protein) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

$689.00 - $1215.00

Specifications

Antigen LRP/MVP (Major Vault Protein) Ab-2
Clone 1032
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Host Species Mouse
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Products 10
Catalog Number Mfr. No. Form Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Form Conjugate Quantity Price Quantity & Availability  
MS664P1ABX
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Epredia
MS664P1ABX
Concentrated Unconjugated 100 μL
Each for $804.00
Only null left
Add to Cart
 
MS664PABX
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Epredia
MS664PABX
Concentrated Unconjugated 200 μL
Each for $1,215.00
Only null left
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MS664P1
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Epredia
MS664P1
Concentrated Unconjugated 500 μL
Each for $703.00
Only null left
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MS664P
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Epredia
MS664P
Concentrated Unconjugated 1 mL
Each for $1,144.00
Only null left
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MS664R7
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Epredia
MS664R7
Prediluted Unconjugated 7 mL
Each for $689.00
Only null left
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MS664B0
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Epredia
MS664B0
Concentrated Biotin 100 μL N/A N/A N/A
MS664B1
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Epredia
MS664B1
Concentrated Biotin 500 μL N/A N/A N/A
MS664B
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Epredia
MS664B
Concentrated Biotin 1 mL N/A N/A N/A
MS664P0
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Epredia
MS664P0
Concentrated Unconjugated 100 μL N/A N/A N/A
MS664R1
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Epredia
MS664R1
Prediluted Unconjugated 1 mL N/A N/A N/A
Description

Description

Major vault protein (MVP) is identical to lung-resistance related protein (LRP). Its shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to progesterone and glucocorticoid receptors are also able to co-immunoprecipitate the MVP. Reportedly, the lung-resistance related protein (LRP) is identical to human MVP. LRP is overexpressed in many neoplastic tissues and cell lines indicating a poor response to chemotherapy.

Host Species: Mouse

Clone: 1032

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells

Molecular Weight: 104-110kDa

Positive Control: SKBR-3 cells, Breast tumors

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)
  • Gel Supershift
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

LRP/MVP (Major Vault Protein) Ab-2
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Mouse
Cancer and Tumor Biology
Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Primary
1032
Monoclonal
RUO
Human, Rat
IgG2a κ
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