p21 WAF1 Ab-11 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results with the Epredia™ p21^WAF1 Ab-11, Mouse Monoclonal Antibody.

Catalog Number	Mfr. No.	Conjugate	Concentration	Quantity
MS891P0	Epredia MS891P0	Unconjugated	200μg/mL	100 μL
MS891PABX	Epredia MS891PABX	Unconjugated	1mg/mL	200 μL
MS891B0	Epredia MS891B0	Biotin	200μg/mL	100 μL
MS891B1	Epredia MS891B1	Biotin	200μg/mL	500 μL
MS891B	Epredia MS891B	Biotin	200μg/mL	1 mL
MS891P1	Epredia MS891P1	Unconjugated	200μg/mL	500 μL
MS891P	Epredia MS891P	Unconjugated	200μg/mL	1 mL
MS891P1ABX	Epredia MS891P1ABX	Unconjugated	1mg/mL	100 μL

Description

p21^WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21^WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21^WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.

Host Species: Mouse

Clone: CP74

Isotype: IgG2b

Species Reactivity: Human and Rat. Others not known.

Epitope: aa 1-80

Immunogen: Full-length human recombinant p21 protein

Molecular Weight: 21kDa

Positive Control: Raji, PC12 cells

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunoprecipitation (Native verified)
• Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: p21superscriptWAF1superscript Ab-11
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Form: Concentrated
• Regulatory Status: RUO
• Target Species: Human, Rat
• Isotype: IgG2b

• Clone: CP74
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Cell Cycle
• Immunogen: Full length human recombinant p21 protein
• Primary or Secondary: Primary