Epredia™ Lab Vision™ pS2/pNR-2 Estrogen-Regulated Protein Ab-2 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Provide accurate, reproducible results with the Epredia™ pS2/pNR-2 Estrogen-Regulated Protein Ab-2, Mouse Monoclonal Antibody.

Supplier:  Epredia™ MS199R1

Catalog No. MS199R1

Description

pS2 is a cysteine-rich, 6.5kDa protein found in both estrogen-dependent (breast tumors) and estrogen-independent tissues (normal stomach mucosa). About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is primarily expressed in estrogen receptor-positive breast tumors.

Host Species: Mouse

Clone: GE2; same as R47/94

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: aa 57-84

Immunogen: A synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCF-YPNTIDVPPEEECEF (aa 57-84) from C-terminus of human pS2 protein

Molecular Weight: 6.5kDa

Positive Control: Normal stomach or breast CA

Cellular Localization: Cytoplasmic Antibody to pS2 is reportedly useful in identifying a subset of estrogen-dependent breast tumors which may respond to endocrine therapy.

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Affinity Purification

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: pS2/pNR-2 Estrogen-Regulated Protein Ab-2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 1 mL
• Research Discipline: Cancer and Tumor Biology
• Target Species: Human
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin)
• Clone: GE2; previously R47/94
• Formulation: Ready-to-use for IHC (UVLP)
• Immunogen: A Synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCF-YPNTIDVPPEEECEF (aa 57-84) from C-terminus of human pS2 protein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Prediluted