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  6. sm (Smith Antigen) Ab-1 Mouse Monoclonal Antibody, Epredia™

sm (Smith Antigen) Ab-1 Mouse Monoclonal Antibody, Epredia™

Catalog No. p-4559706 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
7 mL
Conjugate:
Biotin
Unconjugated
Form:
Concentrated
Prediluted
Concentration:
1mg/mL
200μg/mL
Prediluted
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Catalog No. Quantity Conjugate Form Concentration
MS450P1 500 μL Unconjugated Concentrated 200μg/mL
MS450R7 7 mL Unconjugated Prediluted Prediluted
MS450B0 100 μL Biotin Concentrated 200μg/mL
MS450B1 500 μL Biotin Concentrated 200μg/mL
MS450B 1 mL Biotin Concentrated 200μg/mL
MS450P1ABX 100 μL Unconjugated Concentrated 1mg/mL
MS450PABX 200 μL Unconjugated Concentrated 1mg/mL
MS450P 1 mL Unconjugated Concentrated 200μg/mL
MS450R1 1 mL Unconjugated Prediluted Prediluted
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 9 options available.
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Catalog No. MS450P1 Supplier Epredia Supplier No. MS450P1
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Description

Epredia™ sm (Smith Antigen) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

The sm (Smith) is an autoantigen on a series of particles composed of RNA and protein. Unlike RNP, the sm antigen is resistant to RNase, but partially sensitive to trypsin. It is involved in the pathogenesis of Systemic lupus erythematosus (SLE). Antibodies to sm are found in 20-30% of patients with SLE.

Host Species: Mouse

Clone: Y12

Isotype: IgG3/κ

Species Reactivity: Human, Pig, Rabbit, Rat and Drosophila. Others not known.

Epitope: Not determined

Molecular Weight: ∽25kDa (predominant)

Positive Control: Ls174T cells, Tonsil

Cellular Localization: Nuclear Ab-1 recognizes cross-reactive epitopes on the B'/B and D polypeptides of Sm. Ab-1 precipitates the small nuclear RNAs U1, U2, U4, U5, and U6 providing direct evidence that the Sm antigen resides on all these RNA-protein complexes.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Affinity Purification
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen sm (Smith Antigen) Ab-1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone Y12
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Quantity 500 μL
Regulatory Status RUO
Research Discipline DNA Repair
Primary or Secondary Primary
Target Species Drosophila, Human, Pig, Rabbit, Rat
Form Concentrated
Isotype IgG3 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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