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sm (Smith Antigen) Ab-1 Mouse Monoclonal Antibody, Epredia™
Epredia™ sm (Smith Antigen) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.
$607.00 - $855.00
Specifications
| Antigen | sm (Smith Antigen) Ab-1 |
|---|---|
| Clone | Y12 |
| Applications | Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Host Species | Mouse |
| Catalog Number | Mfr. No. | Form | Conjugate | Quantity | Price | Quantity & Availability | |||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Form | Conjugate | Quantity | Price | Quantity & Availability | |||
|
MS450P1
|
Epredia
MS450P1 |
Concentrated | Unconjugated | 500 μL |
Each for $855.00
|
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MS450R7
|
Epredia
MS450R7 |
Prediluted | Unconjugated | 7 mL |
Each for $607.00
|
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|
MS450B0
|
Epredia
MS450B0 |
Concentrated | Biotin | 100 μL | N/A | N/A | N/A | ||
|
MS450B1
|
Epredia
MS450B1 |
Concentrated | Biotin | 500 μL | N/A | N/A | N/A | ||
|
MS450B
|
Epredia
MS450B |
Concentrated | Biotin | 1 mL | N/A | N/A | N/A | ||
|
MS450P1ABX
|
Epredia
MS450P1ABX |
Concentrated | Unconjugated | 100 μL | N/A | N/A | N/A | ||
|
MS450PABX
|
Epredia
MS450PABX |
Concentrated | Unconjugated | 200 μL | N/A | N/A | N/A | ||
|
MS450P
|
Epredia
MS450P |
Concentrated | Unconjugated | 1 mL | N/A | N/A | N/A | ||
|
MS450R1
|
Epredia
MS450R1 |
Prediluted | Unconjugated | 1 mL | N/A | N/A | N/A | ||
Description
The sm (Smith) is an autoantigen on a series of particles composed of RNA and protein. Unlike RNP, the sm antigen is resistant to RNase, but partially sensitive to trypsin. It is involved in the pathogenesis of Systemic lupus erythematosus (SLE). Antibodies to sm are found in 20-30% of patients with SLE.Host Species: Mouse
Clone: Y12
Isotype: IgG3/κ
Species Reactivity: Human, Pig, Rabbit, Rat and Drosophila. Others not known.
Epitope: Not determined
Molecular Weight: ∽25kDa (predominant)
Positive Control: Ls174T cells, Tonsil
Cellular Localization: Nuclear Ab-1 recognizes cross-reactive epitopes on the B'/B and D polypeptides of Sm. Ab-1 precipitates the small nuclear RNAs U1, U2, U4, U5, and U6 providing direct evidence that the Sm antigen resides on all these RNA-protein complexes.
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunofluorescence
- Affinity Purification
- Electron Microscopy
Note:
USA: RUO; Int'l: RUO
Specifications
| sm (Smith Antigen) Ab-1 | |
| Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| Mouse | |
| DNA Repair | |
| IgG3 κ |
| Y12 | |
| Monoclonal | |
| RUO | |
| Drosophila, Human, Pig, Rabbit, Rat | |
| Primary |
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