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Invitrogen™ Laminin-211 Recombinant Rabbit Monoclonal Antibody (19H2L5)

Catalog No. PI702201
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100 μg
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Catalog No. Quantity
PI702201 100 μg
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Catalog No. PI702201 Supplier Invitrogen™ Supplier No. 702201
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Rabbit, Cat and Bovine Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Laminin-211
Applications Immunocytochemistry
Classification Recombinant Monoclonal
Clone 19H2L5
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2-7.4
Gene Lama2
Gene Accession No. P24043, Q60675
Gene Alias 5830440B04; dy; dystrophia muscularis; Lama2; laminin alpha-2; laminin M; Laminin M chain; laminin subunit alpha 2; laminin subunit alpha-2; laminin, alpha 2; laminin-12 subunit alpha; Laminin-2 subunit alpha; laminin-4 subunit alpha; LAMM; mer; merosin; Merosin heavy chain; mKIAA4087
Gene Symbols Lama2
Host Species Rabbit
Immunogen Protein corresponding to Human LAMA2 (aa 1170-1380).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16773, 3908
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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