Invitrogen™ Laminin beta-3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521514

Catalog No. PIPA521514

Description

Recommended positive controls: A431, NIH-3T3, mouse bone marrow. Predicted reactivity: Mouse (81%), Rat (80%), Bovine (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene.

Specifications

• Antigen: Laminin beta-3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LAMB3
• Gene Alias: AI1A; BM600-125KDA; Epiligrin subunit bata; kalinin B1 chain; Kalinin subunit beta; kalinin-140kDa; LAM5; Lamb3; Laminin B1k chain; laminin beta 3; laminin chain; laminin S B3 chain; laminin subunit beta 3; laminin subunit beta-3; laminin, beta 3; laminin, beta 3 (nicein (125kD), kalinin (140kD), BM600 (125kD)); laminin-5 subunit beta; LAMNB1; Nicein subunit beta; nicein, 125kD; nicein, 125kDa; nicein-125k; nicein-125kDa; RP1-272L16.3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16780, 3914
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.46 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q13751, Q61087
• Gene Symbols: LAMB3
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Laminin beta 3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov