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Invitrogen™ Langerin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA141053

Catalog No. 01-676-651


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Description

Description

This antibody is expected to react with rat samples based on sequence homology.

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Langerin
Polyclonal
Unconjugated
CD207
CD 207 antigen; CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CD207 molecule, langerin; CLEC4K; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerhans cell specific c-type lectin; langerin; RGD1565913
Rabbit
Protein G
RUO
246278, 50489
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 0.05% sodium azide
Q8VBX4, Q9UJ71
CD207
Synthetic peptide corresponding to residues 26-44 of mouse Langerin.
100 μg
Primary
Human, Mouse
Antibody
IgG
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