Invitrogen™ LAP1 Monoclonal Antibody (RL13)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA1074

Catalog No. MA1074

Description

MA1-074 detects lamin associated polypeptide (LAP) 1A, 1B & 1C from rat, human, and mouse samples. This antibody does not cross-react with LAP 2. MA1-074 has been successfully used in Western blot, immunofluorescence, immunohistochemistry, and immunoprecipitation procedures. By Western blot, this antibody detects 3 distinct proteins of molecular weights ~65, ~56 and ~ 51 kDa representing LAP 1A, 1B, and 1C, respectively in rat liver nuclear envelope fractions. Immunofluorescence staining of LAP 1 in rat liver with MA1-074 results in exclusive labeling of the nuclear periphery and exhibits co-localization with lamin staining. The MA1-074 immunogen is pore complex-lamina fraction isolated from rat liver nuclear envelopes.

Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(-1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4).

Specifications

• Antigen: LAP1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q5JTV8, Q5PQX1, Q921T2
• Gene Symbols: TOR1AIP1
• Immunogen: Pore complex-lamina fraction isolated from rat liver nuclear envelopes.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: RL13
• Conjugate: Unconjugated
• Gene: TOR1AIP1
• Gene Alias: lamina-associated polypeptide 1B; Lamina-associated polypeptide 1C; Lamin-associated protein 1B; LAP1; LAP1B; Lap1c; Tor1aip1; torsin 1A interacting protein 1; torsin A interacting protein 1; torsin-1A-interacting protein 1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 208263, 246314, 26092
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid