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Invitrogen™ LARGE Monoclonal Antibody (LARGE-02), PE
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Catalog No. PIMA528610
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100 μg
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Catalog No. Quantity
PIMA528610 100 μg
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Catalog No. PIMA528610 Supplier Invitrogen™ Supplier No. MA528610
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Description

Mouse Monoclonal Antibody

This antibody recognizes human LARGE1, a glycosyltransferase expressed mainly in the Golgi apparatus. Cross reactivity with LARGE2 was not determined.

The LARGE gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LARGE
Applications Flow Cytometry
Classification Monoclonal
Clone LARGE-02
Concentration 0.1 mg/mL
Conjugate PE
Formulation PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Large1
Gene Accession No. O95461
Gene Alias Acetylglucosaminyltransferase-like 1A; acetylglucosaminyltransferase-like protein; Beta-1,3-glucuronyltransferase LARGE; BPFD#36; enr; eosinophil granule major basic protein 1; fg; froggy; glycosyltransferase-like 1A; Glycosyltransferase-like protein; glycosyltransferase-like protein LARGE1; glycosyltransferase-like protein LARGE1; LARGE xylosyl- and glucuronyltransferase 1; Gyltl1a; KIAA0609; large; LARGE xylosyl- and glucuronyltransferase 1; Large1; like-acetylglucosaminyltransferase; like-glycosyltransferase; MBP1; Mbp-1; MDC1D; MDDGA6; MDDGB6; mKIAA0609; myd; myodystrophy; prepro major basic protein 1; Xylosyltransferase LARGE
Gene Symbols Large1
Host Species Mouse
Immunogen Human LARGE1 (amino acids 35-142).
Purification Method Size-exclusion chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9215
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2b
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