LARGE Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-4291	150 μL

Catalog No. 50-173-4291 Supplier Proteintech Group Inc Supplier No. 243071AP150UL

Description

Rabbit Polyclonal Antibody

The LARGE gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Specifications

• Antigen: LARGE
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.23 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: LARGE1
• Gene Accession No.: O95461, Q9Z1M7
• Gene Alias: KIAA0609, LARGE, LARGE1, like glycosyltransferase, MDC1D
• Gene Symbols: Large1
• Host Species: Rabbit
• Immunogen: LARGE Fusion Protein Ag19458
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 16795, 9215
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG