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Invitrogen™ Lass4 Polyclonal Antibody
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Catalog No. PIPA112928
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100 μg
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PIPA112928 100 μg
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Catalog No. PIPA112928 Supplier Invitrogen™ Supplier No. PA112928
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Description

Rabbit Polyclonal Antibody

A suggested positive control for this product is lung or embryo lysate.

The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Lass4
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.08% sodium azide
Gene CERS4
Gene Accession No. Q9HA82
Gene Alias 2900019C14Rik; Ceramide synthase 4; CerS4; FLJ12089; LAG1 homolog, ceramide synthase 4; LAG1 longevity assurance homolog 4; Lass4; longevity assurance homolog 4; Sphingosine N-acyltransferase CERS4; TRAM homolog 1; translocating chain-associating membrane protein homolog 1; Trh1
Gene Symbols CERS4
Host Species Rabbit
Immunogen Synthetic peptide corresponding to human Lass4 protein.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79603
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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