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Invitrogen™ LAT Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA19063

Catalog No. 01-674-647


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Description

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000.

LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. After immunoreceptor triggering, LAT becomes multiply tyrosine-phosphorylated by Syk-, Src-, or Tec-family kinases, providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FcepsilonRI-dependent mast cell activation, as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

LAT
Polyclonal
Unconjugated
LAT
36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; Lat; LAT1; linker for activation of T cells; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells; linker for activation of T-cells family member 1; linker protein; p36-38; pp36
Goat
Ammonium sulfate precipitation
RUO
27040
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
O43561
LAT
Synthetic peptide corresponding to the C terminus amino acids GAPDYENLQELN (aa 251-262).
100 μg
Primary
Human
Antibody
IgG
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