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Invitrogen™ LAT Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA19063
Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000.
LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. After immunoreceptor triggering, LAT becomes multiply tyrosine-phosphorylated by Syk-, Src-, or Tec-family kinases, providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FcepsilonRI-dependent mast cell activation, as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.
Specifications
LAT | |
Polyclonal | |
Unconjugated | |
LAT | |
36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; Lat; LAT1; linker for activation of T cells; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells; linker for activation of T-cells family member 1; linker protein; p36-38; pp36 | |
Goat | |
Ammonium sulfate precipitation | |
RUO | |
27040 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
0.5 mg/mL | |
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
O43561 | |
LAT | |
Synthetic peptide corresponding to the C terminus amino acids GAPDYENLQELN (aa 251-262). | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
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