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Lavendustin A, Tocris Bioscience™

Catalog No. 13311
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13-311 1 mg
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Catalog No. 13-311 Supplier R&D Systems Supplier No. LG5931102
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Description

EGFR, p60c-src inhibitor

Potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 11 nM). Inhibits p60c-src with an IC50 of 500 nM and is selective over PKA, PKC and PI 3-kinase (IC50 > 100 μM).

Chemical Identifiers

CAS 125697-92-9
Molecular Formula C21H19NO6
Molecular Weight (g/mol) 381.384
InChI Key ULTTYPMRMMDONC-UHFFFAOYSA-N
Synonym lavendustin a, unii-3y0g32g2rv, lavendustin a, from streptomyces griseolavendus, benzoic acid,5-2,5-dihydroxyphenyl methyl 2-hydroxyphenyl methyl amino-2-hydroxy, 5-2,5-dihydroxyphenyl methyl 2-hydroxyphenyl methyl amino-2-hydroxybenzoic acid, benzoic acid, 5-2,5-dihydroxyphenyl methyl 2-hydroxyphenyl methyl amino-2-hydroxy, 5-2,5-dihydroxybenzyl 2-hydroxybenzyl amino-2-hydroxybenzoic acid, 5-amino-n-2,5-dihydroxybenzyl-n?-2-hydroxybenzyl salicylic acid, 5-amino-n-2,5-dihydroxybenzyl-n′-2-hydroxybenzyl salicylic acid
PubChem CID 3894
IUPAC Name 5-[(2,5-dihydroxyphenyl)methyl-[(2-hydroxyphenyl)methyl]amino]-2-hydroxybenzoic acid
SMILES C1=CC=C(C(=C1)CN(CC2=C(C=CC(=C2)O)O)C3=CC(=C(C=C3)O)C(=O)O)O

Specifications

Quantity 1 mg
Formula Weight 381.38
Percent Purity >98%
Chemical Name or Material Lavendustin A

Safety and Handling

Recommended Storage Desiccate at -20°C
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