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Invitrogen™ LAX1 Polyclonal Antibody
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Catalog No. PIPA547652
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100 μg
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PIPA547652 100 μg
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Catalog No. PIPA547652 Supplier Invitrogen™ Supplier No. PA547652
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Description

Goat Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

Lymphocyte activation gene 1 (LAX1) is located on chromosome 2p16.1 and encodes an immunoregulatory protein that is expressed primarily on lymphocytes, including T cells, B cells, and other immune cells. LAX1 functions as a negative regulator of lymphocyte activation and signaling, playing a crucial role in maintaining immune homeostasis by attenuating excessive immune responses. It acts by modulating signaling pathways that are initiated through surface receptors on lymphocytes, thereby influencing lymphocyte proliferation, cytokine production, and cellular responses during immune activation. Dysregulation of LAX1 expression or function can lead to autoimmune diseases due to impaired control of immune activation. Research into LAX1 focuses on its potential for therapeutic modulation in autoimmune disorders and its role in balancing immune responses, which is essential for maintaining health and preventing pathogenic immune conditions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LAX1
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Lax1
Gene Accession No. Q8IWV1
Gene Alias A530029E09; E430019B13Rik; LAT-like membrane associated protein; LAX; LAX1; Linker for activation of X cells; lymphocyte transmembrane adapter 1; lymphocyte transmembrane adaptor 1; membrane-associated adapter protein LAX
Gene Symbols Lax1
Host Species Goat
Immunogen E. coli-derived recombinant human LAX1 isoform 1 Asn136-Glu398.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54900
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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