Invitrogen™ LBP Monoclonal Antibody (M330-19)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA140029

Catalog No. 01-676-487

Description

Endotoxin level < 24 EU/mg. The MA1-40029 immunogen is mouse natural and recombinant LBP. MA1-40029 detects LBP from mouse samples. This antibody reacts highly specific with mouse natural and recombinant LBP. The antibody is a type I antibody blocking the LPS binding to LBP. MA1-40029 has been successfully used in FACS and ELISA applications.

The LBP protein is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene.

Specifications

• Antigen: LBP
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.1% BSA and no preservative
• Gene Accession No.: Q61805
• Gene Symbols: LBP
• Immunogen: Murine natural and recombinant LBP.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: ELISA, Flow Cytometry
• Clone: M330-19
• Conjugate: Unconjugated
• Gene: LBP
• Gene Alias: acute phase protein; binds bacterial LPS; BPI fold containing family D, member 2; Bpifd2; hypothetical protein LOC512242; LBP; lipopolysaccharide binding protein; lipopolysaccharide-binding protein; lipopolysaccharide-binding protein LPSBP; LPS-binding protein; LPSBP; Ly88
• Host Species: Rat
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 16803
• Content And Storage: 4°C
• Form: Liquid