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Invitrogen™ LBP Monoclonal Antibody (RR433-8)
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Catalog No. 01676488
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100 μg
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Catalog No. Quantity
01-676-488 100 μg
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Catalog No. 01-676-488 Supplier Invitrogen™ Supplier No. MA140030
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Description

Rat Monoclonal Antibody

Endotoxin level < 24 EU/mg. This antibody reacts highly specific with mouse natural and recombinant LBP. The antibody is a type II antibody blocking the LPS binding to CD14. The MA1-40030 immunogen is mouse natural and recombinant LBP. MA1-40030 detects LBP from mouse samples. MA1-40030 has been successfully used in ELISA, Functional Assays and Western blot applications.

The LBP protein is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LBP
Applications ELISA, Functional Assay, Western Blot
Classification Monoclonal
Clone RR433-8
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and no preservative
Gene LBP
Gene Accession No. Q61805
Gene Alias acute phase protein; binds bacterial LPS; BPI fold containing family D, member 2; Bpifd2; hypothetical protein LOC512242; LBP; lipopolysaccharide binding protein; lipopolysaccharide-binding protein; lipopolysaccharide-binding protein LPSBP; LPS-binding protein; LPSBP; Ly88
Gene Symbols LBP
Host Species Rat
Immunogen Murine natural and recombinant LBP.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16803
Target Species Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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Safety and Handling

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