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Invitrogen™ LCLAT1 Polyclonal Antibody
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Catalog No. PIPA525627
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400 μL
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PIPA525627 400 μL
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Catalog No. PIPA525627 Supplier Invitrogen™ Supplier No. PA525627
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Description

Rabbit Polyclonal Antibody

LCLAT1 Polyclonal Antibody for Western Blot, IHC (P)

Exhibits acyl-CoA:lysocardiolipin acyltransferase (ALCAT) activity; catalyzes the reacylation of lyso-cardiolipin to cardiolipin (CL), a key step in CL remodeling. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Also exhibits 1-acyl-sn-glycerol-3-phosphate acyltransferase activity (AGPAT) activity; converts 1-acyl-sn-glycerol-3- phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3- phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:16620771). Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities (PubMed:19075029). Required for establishment of the hematopoietic and endothelial lineages. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen LCLAT1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene LCLAT1
Gene Accession No. Q3UN02, Q6UWP7
Gene Alias 1-acylglycerol-3-phosphate O-acyltransferase 8; 1-AGP acyltransferase 8; 1-AGPAT 8; 1AGPAT8; Acyl-CoA:lysocardiolipin acyltransferase 1; Agpat8; AI181996; Alcat1; Gm91; HSRG1849; LCLAT1; Lycat; lysocardiolipin acyltransferase 1; RGD1565906; UNQ1849; UNQ1849/PRO3579
Gene Symbols LCLAT1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 296-324 amino acids of human LCLT1.
Purification Method Protein A, Antigen affinity chromatography
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 225010, 253558
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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