Invitrogen™ LEF1 Monoclonal Antibody (E.281.8)

Rabbit Monoclonal Antibody

Supplier:  Invitrogen™ MA514966

Catalog No. PIMA514966

Description

It is not recommended to aliquot this antibody.

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: LEF1
• Classification: Monoclonal
• Concentration: 157 μg/mL
• Formulation: 0.01M HEPES with 100μg/mL BSA, 0.15M NaCl, 50% glycerol and <0.02% sodium azide; pH 7.5
• Gene Accession No.: P27782, Q9QXN1, Q9UJU2
• Gene Symbols: LEF1
• Immunogen: Synthetic peptide corresponding to residues surrounding Pro82 of human LEF1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: E.281.8
• Conjugate: Unconjugated
• Gene: LEF1
• Gene Alias: 3000002B05; AI451430; DKFZp586H0919; FLJ46390; HGNC:6551; HMG Binding Domain; LEF1; Lef-1; lymphoid enhancer binding factor 1; lymphoid enhancer binding factor 1 short isoform; lymphoid enhancer-binding factor 1; OTTHUMP00000219736; OTTHUMP00000219737; T cell-specific transcription factor 1-alpha; TCF10; TCF1ALPHA; TCF1-alpha; TCF7L3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 161452, 16842, 51176
• Content And Storage: -20°C
• Form: Liquid