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LexA DNA-binding Domain Polyclonal Antibody, Active Motif™
SDP

Catalog No. 501993944
Encompass
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100 μL
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50-199-3944 10 μL
50-199-3943 100 μL
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Catalog No. 50-199-3944 Supplier Active Motif Supplier No. 39185
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Description

Rabbit Polyclonal Antibody

E. coli LexA protein inhibits the transcription of the genes belonging to the SOS regulon that are related to DNA repair and cell division by recognizing and binding to the SOS-box sequence. LexA‘s self-protease activity is promoted by RecA protein which, responding to DNA damage, is activated by its binding to single-strand DNA accumulated in the cells. It is cleaved into two fragments and loses its function as a repressor. As the result, the expression of genes belonging to the SOS regulon is induced, and mutagenic activity in the cells are enhanced.

Specifications

Antigen LexA DNA-binding Domain
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation whole serum with 30% glycerol and 0.035% sodium azide; pH
Host Species Rabbit
Immunogen This LexA DNA-binding Domain antibody was raised against recombinant protein corresponding to full-length E. coli LexA.
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Yeast
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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