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LexA DNA-binding Domain Rabbit anti-Yeast, Unconjugated, Polyclonal, Active Motif™ 
Rabbit Polyclonal Antibody
$135.30 - $546.00
Specifications
| Monoclonal or Polyclonal | Polyclonal |
|---|---|
| Primary or Secondary | Primary |
| Antigen | LexA DNA-binding Domain |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
50-199-3944
|
Active Motif
39185 |
10 μL |
Each for $135.30
|
|
50-199-3943
|
Active Motif
39184 |
100 μL |
Each for $546.00
|
|
Description
E. coli LexA protein inhibits the transcription of the genes belonging to the SOS regulon that are related to DNA repair and cell division by recognizing and binding to the SOS-box sequence. LexA‘s self-protease activity is promoted by RecA protein which, responding to DNA damage, is activated by its binding to single-strand DNA accumulated in the cells. It is cleaved into two fragments and loses its function as a repressor. As the result, the expression of genes belonging to the SOS regulon is induced, and mutagenic activity in the cells are enhanced.Specifications
| Polyclonal | |
| Primary | |
| LexA DNA-binding Domain | |
| Unconjugated |
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