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  8. LG 101506, Tocris Bioscience™

LG 101506, Tocris Bioscience™

Catalog No. 350850
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50 mg
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Catalog No. Quantity
35-085-0 50 mg
35-081-0 10 mg
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Catalog No. 35-085-0 Supplier R&D Systems Supplier No. 3508/50
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Description

Selective RXR modulator

Selective RXR modulator (Ki values are 3, 9 and 11 nM for RXRα, RXRβ and RXRγ respectively). Displays poor binding affinity for RAR isoforms (Ki values are 2746, 3516 and >10,000 nM for RARα, RARβ and RARγ respectively). Binding to RXR results in selective activation of RXR:PPARγ, RXR:PPARα and RXR:PPARδ heterodimers.

Chemical Identifiers

CAS 331248-11-4
Molecular Formula C25H34F2O3
Molecular Weight (g/mol) 420.541
InChI Key BHIBZAZKKARFIM-UHFFFAOYSA-N
Synonym 7-3,5-di-tert-butyl-2-2,2-difluoroethoxy phenyl-3-methylocta-2,4,6-trienoic acid
PubChem CID 71433850
IUPAC Name 7-[3,5-ditert-butyl-2-(2,2-difluoroethoxy)phenyl]-3-methylocta-2,4,6-trienoic acid
SMILES CC(=CC(=O)O)C=CC=C(C)C1=CC(=CC(=C1OCC(F)F)C(C)(C)C)C(C)(C)C

Specifications

Quantity 50 mg
Formula Weight 420.53
Percent Purity >98%
Chemical Name or Material LG 101506

Safety and Handling

Recommended Storage Store at +4°C
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