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Tocris Bioscience™ LIH 383
SDP

Catalog No. 80951 Shop All Novus Biologicals Products
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80-951 1 mg
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Catalog No. 80-951 Supplier Tocris Bioscience™ Supplier No. 8095/1

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Description

Atypical chemokine receptor (ACKR3) agonist

LIH 383 is a potent and highly selective atypical chemokine receptor (ACKR3/CXCR7) agonist. LIH 383 competes directly with CXCL12-AF647 and is more potent in inducing β-arrestin recruitment to ACKR3 (EC50 = 0.61 nM) than the full-length chemokine ligands CXCL12 or CXCL11 (EC50 = 1.2 nM and 2.2 nM, respectively). In a rat ex vivo model, LIH383 increases the availability and signaling of opioid peptides at classical receptors.

Specifications

Purity 0.95
CAS 2866266-58-0
Content And Storage Store at -20°C
Molecular Weight (g/mol) 997.23
Quantity 1 mg
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