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LILRB3 Mouse anti-Human, Clone: OTI3G9, liquid, TrueMAB™

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA812163

Encompass_Preferred

Catalog No. 50-168-4432


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Description

Description

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

LILRB3
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
O75022
CD85A, HL9, ILT-5, ILT5, LILRA6, LIR-3, LIR3, PIR-B, PIRB
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
11025
Western Blot
OTI3G9
Unconjugated
LILRB3
Liquid
LILRB3
Human recombit protein fragment corresponding to amino acids 465-631 of human LILRB3 produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
SDS
Documents
Product Certifications
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