Invitrogen™ LIMD1 Polyclonal Antibody

Catalog No.	Quantity
PIPA566671	100 μL

Catalog No. PIPA566671 Supplier Invitrogen™ Supplier No. PA566671

Description

Rabbit Polyclonal Antibody

Immunogen sequence: MDKYDDLGLEA SKFIEDLNMY EASKDGLFRV DKGAGNNPEF EETRRVFATK MAKIHLQQ Highest antigen sequence identity to the following orthologs - mouse 100%, rat 98%.

The Zyxin family of proteins contains five members: Ajuba, Limd1, LPP, TRIP6 and Zyxin. Limd1 (LIM domain-containing protein 1) is a ubiquitously expressed tumor suppressor containing three LIM zinc-binding domains. LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding subdomains, which mediate protein-protein interactions. Limd1 interacts with the proteins SQSTM1, Rb, p62 and TRAF6. Limd1 was first identified when the deletion of its gene was noted in some cervical cancers. Limd1 blocks in vitro and in vivo tumor growth and is downregulated in lung cancer.

Specifications

• Antigen: LIMD1
• Applications: Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: LIMD1
• Gene Accession No.: Q9UGP4
• Gene Alias: AW822033; D9Ertd192e; LIM domain-containing protein 1; LIM domains containing 1; Limd1
• Gene Symbols: LIMD1
• Host Species: Rabbit
• Immunogen: Recombinant Human LIMD1. Recombinant protein control fragment (Product #RP-105303).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8994
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG