LIN28A Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-199-3221	Active Motif 61192	10 μL
50-199-3220	Active Motif 61191	100 μL

Description

Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C. elegans. The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.

Specifications

• Antigen: LIN28A
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q8K3Y3, Q9H9Z2
• Gene ID (Entrez): 79727, 83557
• Immunogen: This LIN28A antibody was raised against a peptide derived from the C-terminal region of human LIN28A.
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: LIN28A

• Concentration: Lot-Specific
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Gene Alias: AL024421; CSDD1; ENSMUSG00000070700; FLJ12457; Gm10299; lin28; lin-28; lin-28 homolog A; lin-28 homolog A (C. elegans); Lin28a; Lin-28A; Protein lin-28 homolog A; RGD1566408; RNA-binding protein lin-28; sb:cb650; si:ch211-232d9.4; similar to RNA-binding protein LIN-28; testis expressed gene 17; Testis-expressed protein 17; Tex17; ZCCHC1; zgc:55584; Zinc finger CCHC domain-containing protein 1; zinc finger, CCHC domain containing 1
• Gene Symbols: LIN28A
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody