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LIN7A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 251501AP150UL

Encompass_Preferred

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Catalog No. 50-173-4751


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Description

Description

Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
Specifications

Specifications

LIN7A
Polyclonal
Unconjugated
LIN7A
hLin 7, lin 7 homolog A (C. elegans), LIN 7A, LIN7, LIN7A, MALS 1, MALS1, Mammalian lin seven protein 1, Protein lin 7 homolog A, Tax interaction protein 33, TIP 33, Veli 1, VELI1, Vertebrate lin 7 homolog 1
Rabbit
Antigen Affinity Chromatography
RUO
108030, 85327, 8825
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O14910, Q8JZS0, Q9Z250
Lin7a
LIN7A Fusion Protein Ag18440
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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