Invitrogen™ LIN7C Polyclonal Antibody

Catalog No.	Quantity
51-560-0	100 μg

Catalog No. 51-560-0 Supplier Invitrogen™ Supplier No. 515600

Description

Rabbit Polyclonal Antibody

LIN7C Polyclonal Antibody for ELISA, ICC/IF, IHC (F), IP, Western Blot

Protein assembly at the post synaptic density (PSD) of neuronal synapses is mediated in part by protein interactions with PDZ (PSD-95/discs large/zona occludens-1) motifs. The Mammalian LIN-7 (MALS) proteins are a family of small synaptic proteins that are the mammalian homologs of LIN-7, a C. elegans protein essential for vulval development. MALS proteins are also known as Veli (Vertebrate Lin-7) proteins. MALS-3 mRNA is most abundant in kidney, followed by brain, liver, thymus and heart. MALS-3 is undetectable in spleen. In cultured cortical neurons, MALS proteins are clustered together with PSD-95 and NMDA-type glutamate receptors. MALS proteins are suggested to have roles in regulating the recruitment of neurotransmitter receptors to the PSD and in the assembly of proteins involved in synaptic vesicle exocytosis and synaptic junctions.

Specifications

• Antigen: LIN7C
• Applications: ELISA, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.25 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% sodium azide; pH 7.4
• Gene: LIN7C
• Gene Accession No.: O88952, Q792I0, Q9NUP9
• Gene Alias: 9130007B12Rik; AI303698; AU019331; AW125731; D2Ertd520e; EGK_06400; fb75b09; FLJ11215; lin 7 homolog c; lin-7 homolog C; lin-7 homolog C (C. elegans); lin-7 homolog C, crumbs cell polarity complex component; LIN-7 protein 3; Lin7c; LIN-7C; lin-7-C; lin7c protein; MALS3; MALS-3; Mammalian lin-seven protein 3; mLin7C; neuroepithelial polarity protein; protein lin-7 homolog C; Protein lin-7-like protein C; Unknown (protein for MGC:140723); Veli3; veli-3; veli-3 protein; vertebrate homolog of C. elegans Lin-7 type 3; vertebrate lin-7 homolog 3; wu:fb75b09; zgc:101881
• Gene Symbols: LIN7C
• Host Species: Rabbit
• Immunogen: Synthetic peptide derived from the C-terminus of the rat Velis-3 (MALS-3) protein.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22343, 485424, 55327, 60442
• Target Species: Canine, Human, Mouse, Monkey, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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