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Invitrogen™ Lipoteichoic Acid Monoclonal Antibody (55)
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Catalog No. 01676525
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01-676-525 1 mL
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Catalog No. 01-676-525 Supplier Invitrogen™ Supplier No. MA140134
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Description

Mouse Monoclonal Antibody

MA1-40134 detects Lipoteichic Acid from gram positive bacterial samples. MA1-40134 has been successfully used in Western blot, ELISA, flow cytometry, immunofluorescence, and Immunohistochemistry (frozen) applications. Positive control: Culture medium of Gram-positive bacteria. Negative control: Culture medium of eukaryotic cells. The MA1-40134 immunogen is a microbial mixture of Streptococcus sobrinus HG961, HG962, HG970, and HG977.

Lipoteichoic acid (LTA) is a glycerol phosphate surface polymer component of the envelope of Gram-positive bacteria. LTA is anchored via its glycolipids to the membrane and carries a polysaccharide chain extending into the peptidoglycan layer of the cell wall. LTA is released spontaneously into the culture medium during growth of gram-positive bacteria. LTA functions as an immune activator with characteristics very similar to lipopolysaccharide (LPS) from Gram-negative bacteria. LTA binds to CD14 and triggers activation predominantly via Toll-like receptor 2. Although LTA is internalized and traffics to the Golgi, the cellular activation in response to LTA occurs at the cell surface.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Lipoteichoic Acid
Applications ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
Classification Monoclonal
Clone 55
Concentration >200 μg/mL
Conjugate Unconjugated
Formulation Tissue culture supernatant with 0.02% sodium azide
Gene Alias LTA
Host Species Mouse
Immunogen Microbial mixture of Streptococcus sobrinus HG961, HG962, HG970, and HG977.
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Bacteria
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG3
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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