Livin Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5694	150 μL

Catalog No. 50-173-5694 Supplier Proteintech Group Inc Supplier No. 275431AP150UL

Description

Rabbit Polyclonal Antibody

The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity. Recently, it has been identified that a novel human inhibitor of apoptosis protein (IAP) family member termed Livin or ML-IAP, which contains a single baculoviral IAP repeat (BIR) domain and a COOH-terminal RING finger domain. Livin gene has two splicing variants that contain open reading frames of 298 and 280 amino acids and both contained a single copy of baculovirus IAP repeat (BIR) and RING domain. Both of the isoforms inhibit TNFa induced apoptosis in Jurkat cells. Livin expression is low in adult tissues. It is relatively expressed at a higher level in developmental tissues and in many cancer cells.

Specifications

• Antigen: Livin
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.53 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: BIRC7
• Gene Accession No.: Q96CA5
• Gene Alias: BIRC7, KIAP, LIVIN, ML IAP, MLIAP, RING finger protein 50, RNF50
• Gene Symbols: BIRC7
• Host Species: Rabbit
• Immunogen: Livin Fusion Protein Ag26737
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 79444
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG