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Invitrogen™ LKB1 Monoclonal Antibody (206R24)
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Catalog No. AHO1392
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100 μg
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Catalog No. Quantity
AHO1392 100 μg
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Catalog No. AHO1392 Supplier Invitrogen™ Supplier No. AHO1392
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Description

Mouse Monoclonal Antibody

LKB1 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LKB1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 206R24
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene STK11
Gene Accession No. D4AE59, Q15831, Q9WTK7
Gene Alias AA408040; CAMK group; CAMKL family; hLKB1; liver kinase B1; Liver kinase B1 homolog; LKB 1; LKB1; LKB-1; LKB1(S); Par-4; PJS; polarization-related protein LKB1; R75140; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11; STK11
Gene Symbols STK11
Host Species Mouse
Immunogen Recombinant fragment of human LKB1 expressed in E. coli.
Purification Method Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20869, 314621, 6794
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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