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Invitrogen™ LMX1A Polyclonal Antibody
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Catalog No. PIPA534470
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100 μg
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PIPA534470 100 μg
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Catalog No. PIPA534470 Supplier Invitrogen™ Supplier No. PA534470
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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat brain tissue lysate. PA5-34470 can be used with blocking peptide PEP-1512.

The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LMX1A
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Lmx1a
Gene Accession No. Q8TE12, Q9JKU8
Gene Alias dr; dreher; LIM homeobox transcription factor 1 alpha; LIM homeobox transcription factor 1, alpha; LIM homeobox transcription factor 1-alpha; LIM/homeobox protein 1.1; LIM/homeobox protein LMX1A; LMX1; LMX-1; Lmx1.1; LMX-1.1; Lmx1a; MGC87616; shaker short-tail; sst
Gene Symbols Lmx1a
Host Species Rabbit
Immunogen A 16 amino acid peptide near the carboxy terminus of human LMX1A.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110648, 289201, 4009
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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