Invitrogen™ LMX1A Polyclonal Antibody

Catalog No.	Quantity
PIPA5115517	100 μL

Catalog No. PIPA5115517 Supplier Invitrogen™ Supplier No. PA5115517

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total LMX1A.

The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.

Specifications

• Antigen: LMX1A
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene: Lmx1a
• Gene Accession No.: Q8TE12, Q9JKU8
• Gene Alias: dr; dreher; LIM homeobox transcription factor 1 alpha; LIM homeobox transcription factor 1, alpha; LIM homeobox transcription factor 1-alpha; LIM/homeobox protein 1.1; LIM/homeobox protein LMX1A; LMX1; LMX-1; Lmx1.1; LMX-1.1; Lmx1a; MGC87616; shaker short-tail; sst
• Gene Symbols: Lmx1a
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human LMX1A(Accession Q8TE12), corresponding to amino acid residues R152-L202.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 110648, 289201, 4009
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG