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LMX1B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. p-7208532 Shop All Proteintech Group Inc Products
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50-173-2086 150 μL
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Catalog No. 50-173-2086 Supplier Proteintech Group Inc Supplier No. 182781AP150UL
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Description

Rabbit Polyclonal Antibody

The LIM homeobox transcription factor 1B (LMX1B) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning; LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.

Specifications

Antigen LMX1B
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.31 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene LMX1B
Gene Accession No. O60663, O88609
Gene Alias LIM/homeobox protein 1.2, LIM/homeobox protein LMX1B, LMX 1.2, LMX1.2, LMX1B
Gene Symbols Lmx1b
Host Species Rabbit
Immunogen LMX1B Fusion Protein Ag13096
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114501, 16917, 4010
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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