Invitrogen™ LOXL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579609

Catalog No. PIPA579609

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: A549 whole cell, HELA whole cell. IHC: human prostatic cancer tissue.

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Specifications

• Antigen: LOXL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Loxl1
• Gene Alias: cross-linking enzyme; LOL; Lox2; LOXL; LOXL1; Lysyl oxidase 2; lysyl oxidase homolog 1; lysyl oxidase like 1; lysyl oxidase-like 1; lysyl oxidase-like protein 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4016
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene Accession No.: Q08397
• Gene Symbols: Loxl1
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LOXL1 (397-425aa AEEKCLASTAYAPEATDYDVRVLLRFPQR).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG