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Invitrogen™ LOXL1 Polyclonal Antibody
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Catalog No. PIPA579609
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100 μg
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PIPA579609 100 μg
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Catalog No. PIPA579609 Supplier Invitrogen™ Supplier No. PA579609
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: A549 whole cell, HELA whole cell. IHC: human prostatic cancer tissue.

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LOXL1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide
Gene Loxl1
Gene Accession No. Q08397
Gene Alias cross-linking enzyme; LOL; Lox2; LOXL; LOXL1; Lysyl oxidase 2; lysyl oxidase homolog 1; lysyl oxidase like 1; lysyl oxidase-like 1; lysyl oxidase-like protein 1
Gene Symbols Loxl1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human LOXL1 (397-425aa AEEKCLASTAYAPEATDYDVRVLLRFPQR).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4016
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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