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Invitrogen™ LOXL3 Polyclonal Antibody
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Catalog No. PIPA545074
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PIPA545074 100 μL
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Catalog No. PIPA545074 Supplier Invitrogen™ Supplier No. PA545074
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Rabbit Polyclonal Antibody

Peptide sequence: AASSGQKKQQ QSKPQGEARV RLKGGAHPGE GRVEVLKAST WGTVCDRKWD Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 93%; Rat: 93%.

LOXL3 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LOXL3
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene LOXL3
Gene Accession No. P58215
Gene Alias Lor2; LOW QUALITY PROTEIN: lysyl oxidase homolog 3; LOXL; Loxl2; Loxl3; Lysyl oxidase homolog 3; lysyl oxidase like 3; lysyl oxidase-like 2; lysyl oxidase-like 3; lysyl oxidase-like protein 3; Lysyl oxidase-related protein 2
Gene Symbols LOXL3
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human LOXL3.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84695
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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