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AdipoGen Loxoribine, 121288-39-9, MFCD00867591, 5 mg
SDP

Supplier:  AdipoGen AGCR13584M005

Encompass_Preferred

MF: C13H17N5O6, MW: 339.3, ≥97%, Appearance: White to off-white powder. Guanosine analog derivatized at position N7 and C8. Very potent immunostimulatory compound that increases cytokine production. Antitumor and antiviral activity compound. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7). Co-incubation with thymidine homopolymer oligodeoxynucleotides (ODN) redirected the stimulatory effect of loxoribine away from TLR7 toward TLR8. Induces autophagy and autophagy-induced cell death in Caco-2 cells. Shows adjuvant activity to increase the effectiveness of vaccines.

Catalog No. 50-117-6103


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