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LP 12 hydrochloride, Tocris Bioscience™

Catalog No. 292550
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Catalog No. Quantity
29-255-0 50 mg
29-251-0 10 mg
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Catalog No. 29-255-0 Supplier R&D Systems Supplier No. 2925/50
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Description

5-HT7 agonist

5-HT7 receptor agonist displaying selectivity over D2, 5-HT1A and 5-HT2A receptors (Ki values are 0.22, 7.3, 52.7 and 326 nM respectively). Induces relaxation of substance P-induced contractions in guinea pig ileum (EC50 = 1.77 μM).

Chemical Identifiers

CAS 1185136-22-4
Molecular Formula C32H40ClN3O
Molecular Weight (g/mol) 518.142
InChI Key XNDUOTNYUWDFKR-UHFFFAOYSA-N
Synonym lp 12 hydrochloride, lp 12 hydrochloride hydrate, 4-2-diphenyl-n-1,2,3,4-tetrahydronaphthalen-1-yl-1-piperazinehexanamide hydrochloride
PubChem CID 56972187
IUPAC Name 6-[4-(2-phenylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide;hydrochloride
SMILES C1CC(C2=CC=CC=C2C1)NC(=O)CCCCCN3CCN(CC3)C4=CC=CC=C4C5=CC=CC=C5.Cl

Specifications

Quantity 50 mg
Formula Weight 518.13
Percent Purity >99%
Chemical Name or Material LP 12 hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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