Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA5107196

Invitrogen™ LRRC33 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA5107196
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA5107196 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA5107196 Supplier Invitrogen™ Supplier No. PA5107196
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Sequence homology: Cow: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 93%; Rat: 100%.

LRRC33 is a key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. It associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. It is able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta and controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3).
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRC33
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene NRROS
Gene Accession No. Q86YC3
Gene Alias E430025L02Rik; ELLP3030; Garpl1; leucine rich repeat containing 33; leucine-rich repeat-containing protein 33; Leucine-rich repeat-containing protein 33^; Lrcc33; Lrrc33; negative regulator of reactive oxygen species; Nrros; RGD1310771; Transforming growth factor beta activator LRRC33; UNQ3030; UNQ3030/PRO9833
Gene Symbols NRROS
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human LRRC33 (aa 359-409).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 375387
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.