Invitrogen™ LRRFIP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578282

Catalog No. PIPA578282

Description

Positive Control: 293T, A431, NCI-H929 Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Leucine-rich repeat FLI-I interacting protein 1 (LRRFIP1/FLAP-1) is a MyD88-interacting signal protein which mediates either induction or repression of TLR signaling. Flap-1 directly interacts with β-catenin and activates β-catenin-dependent transcription activity. Flap-1 or LRRFIP1 was also shown to bind the TNF- -308 promoter polymorphism site, suggesting its possible role in the regulation of TNF- production. FLAP-1 along with LRRFIP2 and FLIIH serve as a balance in coordinating inflammatory response after infection, and may act as a novel target in the control of agonist-induced TLR-mediated inflammatory and autoimmune diseases.

Specifications

• Antigen: LRRFIP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LRRFIP1
• Gene Alias: AU024550; Flap; FLAP (FLI LRR associated protein); FLAP1; flap-1; Fliiap1; FLI-LRR-associated protein 1; GC-binding factor 2; GCF2; GCF-2; H186 FLAP; HUFI1; HUFI-1; leucine rich repeat (in FLII) interacting protein 1; leucine-rich repeat flightless-interacting protein 1; LRR binding FLII interacting protein 1; LRR FLII-interacting protein 1; Lrrfip1; NEDD8-conjugating enzyme; TAR RNA-interacting protein; TRIP
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9208
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q32MZ4
• Gene Symbols: LRRFIP1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human LRRFIP1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG