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Invitrogen™ LRRFIP1 Polyclonal Antibody
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Catalog No. PIPA578282
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100 μL
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PIPA578282 100 μL
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Catalog No. PIPA578282 Supplier Invitrogen™ Supplier No. PA578282
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Description

Rabbit Polyclonal Antibody

Positive Control: 293T, A431, NCI-H929 Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Leucine-rich repeat FLI-I interacting protein 1 (LRRFIP1/FLAP-1) is a MyD88-interacting signal protein which mediates either induction or repression of TLR signaling. Flap-1 directly interacts with β-catenin and activates β-catenin-dependent transcription activity. Flap-1 or LRRFIP1 was also shown to bind the TNF- -308 promoter polymorphism site, suggesting its possible role in the regulation of TNF- production. FLAP-1 along with LRRFIP2 and FLIIH serve as a balance in coordinating inflammatory response after infection, and may act as a novel target in the control of agonist-induced TLR-mediated inflammatory and autoimmune diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRFIP1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene LRRFIP1
Gene Accession No. Q32MZ4
Gene Alias AU024550; Flap; FLAP (FLI LRR associated protein); FLAP1; flap-1; Fliiap1; FLI-LRR-associated protein 1; GC-binding factor 2; GCF2; GCF-2; H186 FLAP; HUFI1; HUFI-1; leucine rich repeat (in FLII) interacting protein 1; leucine-rich repeat flightless-interacting protein 1; LRR binding FLII interacting protein 1; LRR FLII-interacting protein 1; Lrrfip1; NEDD8-conjugating enzyme; TAR RNA-interacting protein; TRIP
Gene Symbols LRRFIP1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human LRRFIP1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9208
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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